Scientist II - Sr. Scientist, CRISPR Specificity & Genomic Safety

Profluent
Emeryville, California, United States
Full Time
On Site
Mid
USD 147,000 – 177,000
Postgraduate Degree
Science & Research Healthcare Life Sciences

Posted 3 days ago

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Excellent 4.7

Job summary

Seeking a Scientist II - Sr. Scientist in CRISPR specificity and genomic safety at Profluent, an AI-driven protein design company. The role involves developing workflows to evaluate off-target effects of gene editing tools, interpreting sequencing data, and collaborating across R&D to improve genome editing safety and efficacy. Requires experience in molecular biology, genome editing, NGS workflows, and bioinformatics.

Responsibilities

Lead the strategy for base editor specificity assessment by building and scaling biochemical and cell-based workflows. Collaborate cross-functionally to generate high-quality datasets that guide editor design and therapeutic program development.

Qualifications

assay development bioinformatics cell culture CRISPR genome editing genomics molecular biology NGS off-target activity analysis workflow optimization

Requires a PhD in a relevant biological science field with 2-4 years of industry experience in genome editing specificity. Must have deep hands-on expertise with CRISPR systems, NGS-based workflows, and mammalian cell culture.

English

Benefits

  • Equity Participation
  • 401(k) With Employer Match
  • Health Insurance
  • Dental Insurance
  • Vision Insurance
  • Generous PTO Policy
  • Professional Development Opportunities

Company

Profluent

Profluent

linkedin
Biotechnology Research
Location
Emeryville, California, United States

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Excellent 4.7
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